The Anaphylaxis Campaign (www.anaphylaxis.org.uk ) have reported that Mylan UK has recently received an approval for a variation to the administration of EpiPen® and EpiPen® Junior adrenaline auto-injector.
There is no change to the device or the drug (adrenaline); the change is in the instructions for use as outlined below:
· Reduced injection time from 10 to 3 seconds – this is based on research confirming delivery of adrenaline for 3 seconds is sufficient.
· Removal of the massage step after the injection – this step has been removed to simplify the process of administering EpiPen® or EpiPen® Junior.
The changes are aimed to improve patient compliance.
It is important to remember that, the effectiveness of the EpiPen® and EpiPen® Junior will not be impacted regardless of whether it is held for 3 or 10 seconds.
We expect EpiPen® and EpiPen® Junior with the 3-second label to enter pharmacies in the UK from November 2017 onwards. There may still be some EpiPen® and EpiPen® Junior with the 10 second label available on the market.